Genetic Relationships between Clinical Isolates of Streptococcus pneumoniae , Streptococcus oralis , and Streptococcus mitis : Characterization of “Atypical” Pneumococci and Organisms Allied to S. mitis Harboring S. pneumoniae Virulence Factor-Encoding Genes

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Genetic relationships between clinical isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: characterization of "Atypical" pneumococci and organisms allied to S. mitis harboring S. pneumoniae virulence factor-encoding genes.

The oral streptococcal group (mitis phylogenetic group) currently consists of nine recognized species, although the group has been traditionally difficult to classify, with frequent changes in nomenclature over the years. The pneumococcus (Streptococcus pneumoniae), an important human pathogen, is traditionally distinguished from the most closely related oral streptococcal species Streptococcus...

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Susceptibilities of oral and nasal isolates of Streptococcus mitis and Streptococcus oralis to macrolides and PCR detection of resistance genes.

The susceptibility of viridans group streptococci to macrolides was determined. Thirteen isolates (17%) were resistant to erythromycin. Five strains carried an erm gene that was highly homologous to that in Tn917. Four strains had mefE genes that coded erythromycin efflux ability.

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Parallel Evolution of Streptococcus pneumoniae and Streptococcus mitis to Pathogenic and Mutualistic Lifestyles

The bacterium Streptococcus pneumoniae is one of the leading causes of fatal infections affecting humans. Intriguingly, phylogenetic analysis shows that the species constitutes one evolutionary lineage in a cluster of the otherwise commensal Streptococcus mitis strains, with which humans live in harmony. In a comparative analysis of 35 genomes, including phylogenetic analyses of all predicted g...

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rpoB mutations in Streptococcus mitis clinical isolates resistant to rifampin.

Activity of rifampin against 129 Streptococcus mitis isolates obtained from patients with hematologic cancer was investigated. One hundred twenty-five strains were susceptible to rifampin, and 4 were resistant (MIC = 32 to 64 microg/ml). Resistance to rifampin was related to mutations in the rpoB gene: His(526)Asn in three strains and His(526)Asp in one strain.

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Susceptibility testing of Streptococcus mitis group isolates.

BACKGROUND & OBJECTIVES Suppurative oral and maxillofacial infections are usually mixed infections due to aerobic and anaerobic bacteria, most frequently by oral streptococci and antimicrobial treatment is necessary for such infections. The aim of this study was to investigate the antimicrobial susceptibility of Streptococcus mitis group strains isolated from Romanian patients with different or...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 2000

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.68.3.1374-1382.2000